US researchers have updated their recommendations for preventing surgical site infections, advising that antibiotics given before and during surgery should be discontinued immediately after a patient’s incision is closed. The recommendations, published in the journal Infection Control and Hospital Epidemiology, were developed by a panel of experts from five medical organizations led by the Society for Healthcare Epidemiology of America.
The researchers found that continuing antibiotics after a patient’s incision has been closed, even if it has drains, does not prevent surgical site infections. In fact, it increases the patient’s risk of C. difficile infection, which causes severe diarrhea, and antimicrobial resistance. The updated guidelines provide evidence-based strategies for preventing infections for all types of surgeries.
Surgical site infections (SSIs) are a significant problem in healthcare, with an estimated 300,000 cases occurring each year in the United States alone. SSIs can lead to prolonged hospital stays, increased healthcare costs, and even death. Antibiotics have been used to prevent SSIs for decades, but there is growing concern about their overuse and the development of antimicrobial resistance.
The updated recommendations emphasize the importance of a comprehensive approach to preventing SSIs, including proper hand hygiene, appropriate surgical technique, and judicious use of antibiotics. The panel of experts also recommended that healthcare facilities establish surveillance systems to monitor SSIs and track antibiotic use.
“Preventing SSIs requires a multidisciplinary approach that involves everyone from surgeons to nurses to infection preventionists,” said Dr. Keith Kaye, President of the Society for Healthcare Epidemiology of America. “By following these evidence-based recommendations, we can reduce the incidence of SSIs and help preserve the effectiveness of antibiotics.”
The panel of experts acknowledged that there may be situations where continued antibiotic prophylaxis after surgery is necessary, such as in patients with a high risk of infection or in complex surgeries. In these cases, the duration of prophylaxis should be as short as possible and based on the patient’s individual risk factors.
The updated guidelines also addressed the issue of preoperative antibiotic selection. The panel of experts recommended that antibiotics be selected based on the type of surgery and the local microbiology. They also advised against the routine use of vancomycin or other broad-spectrum antibiotics for surgical prophylaxis, as this can contribute to the development of antimicrobial resistance.